About Our Project
Southeast Asia (SEA) has the longest record of human habitation outside of Africa for nearly two million years following the arrival of ancient human, the Javanese (Homo erectus). However, there are still many questions concerning the Southeast Asians, in particular the Orang Asli of Peninsular Malaysia that has yet to be answered.
Realizing the need of this, a group of researcher from Unviersiti Teknologi MARA (UiTM), Universiti Sains Malaysia (USM), and Universiti Kebangsaan Malaysia (UKM) has gathered their field of expertise to come up with the "Evolutionary Genomics and Anthropological Approaches on the Endangered Malaysian Orang Asli Populations: Towards Ensuring their Sustainability" programme. This project is funded under the Long Term Research Grant (LRGS) which was awarded by the Ministry of Higher Education Malaysia.
Realizing the need of this, a group of researcher from Unviersiti Teknologi MARA (UiTM), Universiti Sains Malaysia (USM), and Universiti Kebangsaan Malaysia (UKM) has gathered their field of expertise to come up with the "Evolutionary Genomics and Anthropological Approaches on the Endangered Malaysian Orang Asli Populations: Towards Ensuring their Sustainability" programme. This project is funded under the Long Term Research Grant (LRGS) which was awarded by the Ministry of Higher Education Malaysia.
Methods
- Ethical approval
- Genomic DNA extraction and whole genome sequencing
- Quality assessment, whole genome assembly and alignment
- Variant discovery and quality score recalibration
- Determination of allele frequencies and clinical annotation of genome variants
- Hardy Weinberg Equilibrium analysis and visualization of LD and haplotype maps.
Softwares
Sample type
- Raw blood
Usage:
- EDTA Blood Tube: Whole Genome Sequencing
- Plain Blood Tube: Biochemical test (Serum)
A collaborative effort between